What are the consequences of significant aortic regurgitation?

In this video, you will learn about the consequences of significant aortic regurgitation (AR) and the subsequent deterioration of left ventricular function over time. The timing of surgical intervention, such as aortic valve replacement, plays a crucial role in the patient's prognosis. Initially, the left ventricle can adapt to the increased volume load caused by AR, but as the disease progresses, the ventricle becomes irreversibly dysfunctional due to continued left ventricular dilatation and volume overload. This is why the timing of surgery in patients with significant AR is so important.